Malakoplakia Case 189 : 無料・フリー素材/写真
Malakoplakia Case 189 / Pulmonary Pathology Society
| ライセンス | クリエイティブ・コモンズ 表示-継承 2.1 |
|---|---|
| 説明 | Malakoplakia, a condition often associated with immunodeficiency and characterized by abnormal macrophage function consists of sheets of large histiocytes in response to a bacterial infection. It represents a relatively ineffective inflammatory response because of persistence of bacteria and/or bacterial degradation products within the histiocytes. In the lungs it is almost always caused by infection with Rhodococcus equi but it may be caused by other bacteria. Malakoplakia is morphologically very similar to Mycobacterium avium complex infection in AIDS patients and to Whipples disease and lepromatous leprosy. The distinguishing and diagnostic feature of malakoplakia is the presence of small intracellular concentrically calcified structures called Michaelis-Gutman bodies (MG bodies). MG bodies also contain stainable iron. Intracytoplasmic calcifications not having the typical appearance of MG bodies may also be present.In this low magnification photomicrograph the lung tissue to the right is occupied by a mixed inflammatory cellualr infiltrte with a predominance of large histiocytes. Relatively uninvolved lung tissue is seen at the left. |
| 撮影日 | 2011-06-09 14:54:27 |
| 撮影者 | Pulmonary Pathology Society , USA |
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| カメラ | DS-Fi1-L2 , Nikon |
| 露出 | 0.006 sec (1/180) |