Endogenous lipid pneumonia : 無料・フリー素材/写真
Endogenous lipid pneumonia / Pulmonary Pathology Society
| ライセンス | クリエイティブ・コモンズ 表示-継承 2.1 |
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| 説明 | Endogenous lipid pneumonia, sometimes called obstructive pneumonia, develops from the accumulation of lipid-rich debris from destroyed alveolar cells, typically in the setting of bronchial obstruction or chronic inflammation. Unlike exogenous lipid pneumonia, which results from aspiration of external lipid materials, endogenous lipid pneumonia arises from endogenous lipid sources within the lung parenchyma.The pathogenesis involves disruption of normal alveolar cell turnover and lipid metabolism. Bronchial obstruction leads to impaired clearance mechanisms and accumulation of cellular debris distal to the obstruction. Chronic inflammation damages alveolar epithelial cells and type II pneumocytes, releasing cholesterol and phospholipids into the alveolar spaces. These lipids are then phagocytosed by alveolar macrophages, which become engorged and transform into characteristic foamy macrophages. Touton giant cells are present in this image. Cholesterol crystals are sometimes seen.Image contributed by Dr. Yale Rosen - @yro854 |
| 撮影日 | 2009-08-01 09:31:51 |
| 撮影者 | Pulmonary Pathology Society , USA |
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